Adaptation to Choline Deprivation: Choline Redistribution and Choline Storage
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چکیده
منابع مشابه
3 . 2 Choline and Its Products Acetylcholine and Phosphatidylcholine Choline
Choline, a quaternary amine obtained largely from the diet but also synthesized in the brain and, especially, liver, is an essential precursor of the neurotransmitter acetylcholine (ACh) and of the major membrane constituent phosphatidylcholine (PC). Plasma choline concentrations can vary over a fivefold range depending on the choline contents of the foods being digested. Since choline readily ...
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Choline is a water-soluble nutrient that is often grouped with the vitamin B complex. However, its functions suggest it is more than just another vitamin. Choline is crucial for the normal function of all cells (Zeisel and Blusztajn, 1994). It is needed for the structural integrity and signaling functions of cell membranes; it directly affects cholinergic neurotransmission; it is the major sour...
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Choline saccharinate and choline acesulfamate are two examples of hydrophilic ionic liquids, which can be prepared from easily available starting materials (choline chloride and a non-nutritive sweetener). The (eco)toxicity of these ionic liquids in aqueous solution is very low in comparison to other types of ionic liquids. A general method for the synthesis and purification of hydrophilic ioni...
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The construction and performance of an amperometric microbiosensor for the determination of choline chloride by immobilizing choline oxidase on a cellulose acetate membrane are described. The procedure of choline determination involved the electrochemical detection of enzymatically generated hydrogen peroxide. This microsensor has a linear response between 0.038-0.1 mM choline chloride. The...
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Choline synthesis in the rat is intimated by the fact that methionine can replace choline in preventing fatty livers (l), and by the observation that labeled methyl groups can be transferred from methionine to choline (2). However, the development of fatty livers (3) and of hemorrhagic kidneys (4) and the restricted growth (5, 6) in rats on low choline diets all suggest that preformed choline m...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a86-a